If you know you have a thin uterine lining, it is essential you work to nourish and increase the endometrium once again. It may also be helpful to learn about using natural therapies to aid in healing damaged tissues. If damaged tissues are not repaired, they may never function properly ever again. If you are going for IUI or IVF and the uterine lining is not thick enough, those procedures are canceled.
Get moving. Exercise!
No matter the reason for thin uterine lining, be sure to move your body every day. If you have a desk job, this is very important. Sitting all day compresses the reproductive organs. Walking is straightforward and moves the hips, allowing higher blood flow to the uterus. Fertility yoga is also an excellent way to enhance circulation to the reproductive organs. It helps to reduce stress, which helps to keep the uterine artery open. Be sure you are moving and stretching your legs, hips, abdomen and back to provide adequate circulation to the reproductive organs.
Prepare with a Fertility Cleanse
An official journal of the United States and Canadian Academy of Pathology, Inc., Modern pathology, identifies how repeated use of synthetic hormones and medications for fertility can cause a thin uterine lining. If you have used Clomid or hormonal birth control in the past, especially long-term, give your body at least a 3-6-month break from those medications to restore the lining of the uterus, and prepare for pregnancy. Consider the benefits of performing a Fertility Cleanse at that time. Specific herbs in the Fertility Cleanse aid in restoring hormonal balance and improving uterine health. To aid the body in cleansing, choose to eat whole organic foods, use all-natural home care and body products and learn what endocrine disruptors are so that you can avoid them. A modern Mayr therapy is an ideal way to do such fertility clearance. As recommended by the World Health Organization a couple going for conception should treat their body the way they would treat their house when expecting a distinguished guest.
Modalities for improving refractory endometrium
Numerous treatments have been tried to improve refractory endometrium, but success is limited. Currently, evidence-based medicine has not validated any specific treatment. The most popular ongoing therapies are the following:
Intra-uterine granulocyte colony-stimulating factor
The human endometrium expresses granulocyte colony-stimulating factor mRNA and its receptor throughout the menstrual cycle. G-CSF may, therefore, play a physiological role in endometrial development through interactions with other cytokines and ovarian steroid hormones. Estrogen may be necessary to provide nutrition to the endometrium after stimulation by G-CSF.
A dose of G-CSF or recombinant G-CSF is administered in the proliferative phase, on the day of human chorionic gonadotropin administration, on the day of ovulation or day of administration of progesterone.
Extended oestrogen support
Endometrial thickness improved by extending the estrogen administration for 14-82 days, in HRT-FET cycles.
Human chorionic gonadotropin priming in the follicular phase
A study by Papanikolaou and his group suggested that 150 IU HCG given daily for seven days, starting from day 8 to 9 of estrogen to improve endometrial thickness. Their rationale was that HCG administration might have a positive effect on the endometrial HCG/LH receptors.
Drugs that increase endometrial blood flow have been administered individually or in combination to improve endometrial thickness y different groups. They include Pentoxyfilline 800 mg/day and tocopherol 1000 mg/day given over several months, sildenafil 100 mg/day given as vaginal pessary, l-arginine 6 g/day, and low dose aspirin 75 mg/day. None of these therapies has met with much success.
Occasional reports of IU autologous platelet-rich plasma infusion, IU administration of bone marrow stem/progenitor cells, luteal phase support with GnRH agonist, pelvic floor Neuromuscular electrical stimulation for improving endometrial are in the literature, but none of the treatments has been substantiated. In our centre, we have made few successful attempts with the use of IU administration of PRP, as well as the use of Bioelectrical Stimulation (BES) administered to patients during detoxification at the Mart-life Detox clinic.
Regenerative medicine – many research units are working on the use of the stem cell therapy for regeneration of the endometrium. So far, it remains a research protocol and has not cleared for routine clinical use.
In general, we have combined a number of the above protocols to help several patients with poor endometrial lining conceive.
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